Classical Ayurvedic texts recommend Panchakarma at the junctions of the seasons, when the doshas accumulated in one season are ready to be cleared. In practice, late monsoon transitioning into early autumn suits Virechana for Pitta imbalance, while early spring suits Vamana for Kapha imbalance. The body is more receptive to these therapeutic interventions when the weather is mild, digestion is steady, and the person can dedicate time to rest and recovery. Practitioners should avoid scheduling Panchakarma during periods of extreme heat or cold, as these conditions compromise the body's capacity to respond optimally to treatment. A thorough consultation before beginning any Panchakarma protocol ensures that the timing aligns with the individual's constitution, current health status, and seasonal context, maximizing both safety and efficacy.